DelveInsight’s, “Alzheimer’s Disease Pipeline Insights 2023” report provides comprehensive insights about 150+ companies and 160+ pipeline drugs in Alzheimer’s Disease pipeline landscape. It covers the Alzheimer’s Disease pipeline drug profiles, including Alzheimer’s Disease clinical trials and nonclinical stage products. It also covers the Alzheimer’s Disease therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
To explore more information on the latest breakthroughs in the Alzheimer’s Disease Pipeline treatment landscape of the report, click here @ Alzheimer’s Disease Pipeline Outlook
Key Takeaways from the Alzheimer’s Disease Pipeline Report
For further information, refer to the detailed Alzheimer’s Disease Unmet Needs, Alzheimer’s Disease Market Drivers, and Alzheimer’s Disease Market Barriers, click here for Alzheimer’s Disease Ongoing Clinical Trial Analysis
Alzheimer’s Disease Overview
Alzheimer’s disease is a brain disorder that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks. In most people with the disease — those with the late-onset type symptoms first appear in their mid-60s. Early-onset Alzheimer’s occurs between a person’s 30s and mid-60s and is very rare. Alzheimer’s disease is the most common cause of dementia among older adults.
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Alzheimer’s Disease Emerging Drugs Profile
Donanemab is a humanized IgG1 antibody directed at an N-terminal pyroglutamate Aβ epitope that is present only in established plaques. It is specific for this epitope and shows no off-target binding to other Aβ species, neurotransmitters, or their receptors and has no known symptomatic effect. In a phase 1a study involving patients with amyloid-positive prodromal-to-moderate Alzheimer’s disease, the safety, pharmacokinetics, and pharmacodynamics of donanemab were assessed after the administration of multiple doses.
Masitinib (AB1010) is an oral tyrosine kinase inhibitor that has demonstrated neuroprotective action in neurodegenerative diseases via inhibition of mast cell and microglia/macrophage activity, possibly by switching the neuroimmune system from a neurotoxic state towards a neuroprotective state through remodeling of the neuronal microenvironment.The rationale to use masitinib in Alzheimer’s disease patients is supported by preclinical evidence demonstrating that the pharmacological action of masitinib in mast cells can restore normal spatial learning performance in a mouse model of Alzheimer’s disease and promotes recovery of synaptic markers. Currently, the drug is in Phase III stage of Clinical trial evaluation for the treatment of Alzheimer Disease.
XPro1595 is a next-generation inhibitor of tumor necrosis factor (TNF) that uses a dominant-negativeTNF technology that is very different from approved TNF inhibitors that block the effects of both soluble and trans-membrane TNF. Pegipanermin neutralizes soluble TNF, without affecting trans-membrane TNF or TNF receptors. XPro1595 could have substantial beneficial effects in patients with Alzheimer’s and other neurodegenerative diseases by decreasing neuroinflammation. Currently the drug is in Phase II stage of Clinical trial evaluation for the treatment of Alzheimer’s disease.
Dive deep into rich insights for drugs for Alzheimer’s Disease Market Drivers and Alzheimer’s Disease Market Barriers, click here @ Alzheimer’s Disease Unmet Needs and Analyst Views
Alzheimer’s Disease Pipeline Therapeutics Assessment
There are approx. 150+ key companies which are developing the therapies for Alzheimer’s disease. The companies which have their Alzheimer’s disease drug candidates in the most advanced stage, i.e. Preregistration include, Eli Lilly and Company.
Scope of the Alzheimer’s Disease Pipeline Report
Got Queries? Find out the related information on Alzheimer’s Disease Mergers and acquisitions, Alzheimer’s Disease Licensing Activities @ Alzheimer’s Disease Emerging Drugs, and Recent Trends
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About Us
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