New York, USA – March 21, 2022 – Though siRNA-induced RNAi responses have great prospects to treat varieties of human diseases from cancer to pandemic viral outbreaks, siRNAs, before becoming effective drugs, must overcome a billion years of evolutionary defenses designed to prevent invading RNAs from getting to the inside of cells. BOC Sciences, a leading innovator in RNAi technologies, generates numerous siRNA conjugates that are applicable for delivering diversified drugs.
The GalNAc-siRNA conjugate is a representative of BOC Sciences’ abundant drug delivery systems. Technicians of BOC Sciences can synthesize siRNA based on the target gene and then conjugate it with high-quality GalNAc to create GalNAc-siRNA conjugates. The whole process, including siRNA design, synthesis, purification, characterization, siRNA and GalNAc conjugation, and final characterization are all conducted by BOC Sciences alone under a high standard of quality supervision.
The GalNAc-siRNA conjugates provided by BOC Sciences are multivalent, indicating that multiple GalNAc molecules are clustered and conjugated to one siRNA molecule. This setup guarantees a high binding affinity of the interaction between the asialoglycoprotein receptor and the GalNAc ligand, thereby promoting the efficiency of siRNA delivery to the liver.
Apart from the GalNAc-siRNA conjugate, BOC Sciences also owns antibody-siRNA conjugate (ARC) which is another crucial drug delivery strategy in the pharmaceutical industry. The ARC development is still at a very early stage facing several obstacles like low efficiency in internalization and the existence of immune response. To get over the difficulties, BOC Sciences makes the most of its strengths in antibody development, siRNA synthesis, and conjugation techniques. Specifically, BOC Sciences now employs humanized antibodies or Fab fragments, endosomolytic agents, and chemically-modified siRNAs to further optimize ARCs.
GalNAc-siRNA conjugates and ARCs partially present BOC Sciences’ advanced drug delivery systems. “Our exosomes, liposomes and many other siRNA conjugates are all winning worldwide approval for their unequaled quality,” a technical consultant expressed his ambition, “Of course, we are super proud of them but our colleagues are looking for greater breakthroughs nevertheless.”
Highlights of BOC Sciences’ drug delivery system:
• High-quality raw materials
• Free design
• Strict QA and QC
• Advanced analytical equipment
• 1 on 1 customer service
• Competitive price
• Fast delivery
More information about the world-leading biotech company and its RNA drug delivery systems can be reached at https://rna.bocsci.com.
About
BOC Sciences is one of the top life science companies concentrating on RNAi technologies. Its sub-brand BOC RNA has carried out comprehensive RNA research regarding DNA/RNA synthesis reagents, siRNA products, RNA drug delivery systems, etc. Up to now, BOC Sciences has served numerous disease treating programs.
Media ContactCompany Name: BOC SciencesContact Person: Alex BrownEmail: Send EmailPhone: 1-631-485-4226Country: United StatesWebsite: https://rna.bocsci.com
